The various processes by which antibodies may regulate immune responses. At a simple level, secreted antibody neutralises the antigen with which it reacts thus preventing further antigenic stimulation of the antibody-producing clone. At a more complex level, anti-idiotype antibodies can be shown to develop against the first antibodies in some cases, and perhaps further anti-idiotype antibodies against them. This is the main concept of the immunological network theory.

Dictionary of molecular biology. 2004.

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